Construction of Genetic Linkage Maps in Multiparental Populations

Construction of multilocus genetic linkage maps in humans.

Human genetic linkage maps are most accurately constructed by using information from many loci simultaneously. Traditional methods for such multilocus linkage analysis are computationally prohibitive in general, even with supercomputers. The problem has acquired practical importance because of the current international collaboration aimed at constructing a complete human linkage map of DNA mark...

Lecture Notes on Construction of Genetic Linkage Maps

Linkage Analysis and Map Construction in Genetic Populations of Clonal F1 and Double Cross

In this study, we considered four categories of molecular markers based on the number of distinguishable alleles at the marker locus and the number of distinguishable genotypes in clonal F1 progenies. For two marker loci, there are nine scenarios that allow the estimation of female, male, and/or combined recombination frequencies. In a double cross population derived from four inbred lines, fiv...

Robustness of linkage maps in natural populations: a simulation study.

In a number of long-term individual-based studies of vertebrate populations, the genealogical relationships between individuals have been established with molecular markers. As a result, it is possible to construct genetic linkage maps of these study populations by examining the co-segregation of markers through the pedigree. There are now four free-living vertebrate study populations for whom ...

Multiparental Populations: A Call for Papers

s due: October 30, 2016 Manuscripts due: January 5, 2017 Manuscripts submitted after the due date, or without the presubmission abstract, will be considered for publication in the ongoing MPP series, butmay not be published simultaneously with the promotional burst of articles. If youhaveanyquestions,pleaseE-mail the editorial offices: [email protected] or [email protected]...